… Rho-associated coiled-coil containing kinase (ROCK)-2 is an … heart, monocytes, or other
bone marrow-derived cells (n = 5, Figure … cholesterol transport and cholesterol efflux, 34 ROCK2-…

… two isoforms of Rho-associated coiled-coil containing kinase (… of atherosclerotic lesions in
Ldlr − / − mice fed with high-fat … in bone marrow-derived cells leads to increased cholesterol …

… atherosclerosis develops due to progressive accumulation of … mRNA expression of the
cholesterol efflux transporters ATP-… with the rho-associated coiled coil kinase (ROCK)1/2 inhibitor…

… A Rho-associated coiled-coil kinase (ROCK) is identified as … lesions of atherosclerosis and
the formation of foam cells. The … mutations in ROCK2 can lead to increased kinase activity [9]. …

… Rho-associated coiledcoil-containing kinase 2 deficiency in bone marrowderived cells leads
to increased cholesterol efflux and decreased atherosclerosis. Circulation 2012; 126: 2236-…

… ROCK1 in bone marrow-derived cells retards atherosclerosis … -mediated cholesterol efflux,
thus favoring foam cells formation … /ROCK signaling leads to atherosclerosis development and …

… role of Rho-associated coiled-coil containing kinase (ROCK) … , genetic-induced model of
atherosclerosis, or carotid artery … Bone marrow-derived ROCK1-deficient macrophages have …

… atherosclerosis is also an epigenetic disease with the interplay of multiple epigenetic
mechanisms. The epigenetic basis of atherosclerosis … ), in atherosclerotic plaque development …

… Rho-associated coiled-coil-containing protein kinase (ROCK… Due to its centrality in most
cellular events, robust … and cubulin, members of the low-density lipoprotein receptor family that …

… cells (HUVECs) are important features of atherosclerosis (AS)… blot analysis or enzyme‑linked
immunosorbent assay (ELISA)… ‑20a‑5p and Rho‑associated coiled‑coil kinase 2 (ROCK2) …